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Noi perspective terapeutice în insuficienţa cardiacă congestivă la copil

  • Subiect: The prevalence of congestive heart failure is progressively increasing and despite recent advances in therapeutics, there is a continuing need for novel effective therapies. New, investigational treatment strategies include inotropic drugs, neurohormonal antagonists, anticytokine and anti-inflammatory strategies, hormonal therapies. Current positive inotropes (eg, dobutamine and phosphodiesterase inhibitors) provide symptomatic relief, but newer agents may have a better adverse effect profile. Angiotensin-converting enzyme (ACE) inhibitors should remain first-line treatment with angiotensin receptor blockers used in ACE inhibitor-intolerant patients. Many new neurohormonal antagonists have recently been investigated and eplerenone has demonstrated clinical benefit. New hormonal, anticytokine, and anti-inflammatory therapies have shown benefit in small trials, but results in larger trials have been disappointing. Other approaches are currently being tested in large trials that will clarify their role.
  • Limba de redactare: română
  • Secţiunea: Medicină
  • Vezi publicația: Satu Mare - Studii şi Comunicări
  • Editura: Editura Muzeului Sătmărean
  • Loc publicare: Satu Mare
  • Anul publicaţiei: 2007
  • Referinţă bibliografică pentru nr. revistă: VIII; anul 2007; seria Ştiinţele Naturii
  • Paginaţia: 230-236
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